The accuracy of coronary CT angiography (CCTA) & statin regression trials

CCTA Coronary CT angiography Coronary CT angiography accuracy Spatial resolution of CCTA Z axis resolution of CCTA Axial resolution of CCTA Temporal resolution of CCTA coronary CTA coronary plaque coronary plaque regression statin plaque regression statins and coronary calcium statins and CAC score coronary artery calcium score CAC score Agatston score calcified plaque volume CPV non-calcified plaque volume NCPV total plaque volume TPV PARADIGM study PARADIGM trial CCTA plaque progression CCTA plaque quantification serial CCTA coronary plaque volume statin trials statins and atherosclerosis statins and plaque stabilization statins increase calcium score plaque stabilization hypothesis coronary calcification vascular calcification vascular smooth muscle cells VSMC calcification mevalonate pathway HMG-CoA reductase geranylgeranyl pyrophosphate geranyl PP protein prenylation G protein prenylation statin mechanism CoQ10 dolichol heme A insulin receptor glycosylation statins and diabetes CCTA resolution spatial resolution CCTA temporal resolution CCTA axial resolution CCTA blooming artifact calcium blooming artifact CCTA artifact CCTA reproducibility scan rescan variability coefficient of repeatability CoR minimal detectable change MDC individual MDC group MDC plaque measurement error algorithmic drift AI plaque quantification Cleerly HeartFlow QAngio coronary imaging atherosclerosis imaging cardiology lecture preventive cardiology statin controversy Malcolm Kendrick